{"id":174,"date":"2021-05-24T21:15:54","date_gmt":"2021-05-24T21:15:54","guid":{"rendered":"https:\/\/www.vivebiotech.com\/?page_id=174"},"modified":"2026-02-04T10:24:25","modified_gmt":"2026-02-04T09:24:25","slug":"optimizacion","status":"publish","type":"page","link":"https:\/\/www.vivebiotech.com\/es\/tecnologia\/optimizacion\/","title":{"rendered":"Optimizaci\u00f3n"},"content":{"rendered":"

Optimizaci\u00f3n<\/h1>\n
VIVEbiotech cuenta con departamentos dedicados al Desarrollo de Proceso Upstream (USP) y Desarrollo de Proceso Downstream (DSP) centrados en la optimizaci\u00f3n de procesos, con el objetivo de ofrecer una producci\u00f3n eficiente, escalable y que cumpla con las regulaciones para proporcionar a nuestros\/as clientes\/as vectores funcionales y rentables para la administraci\u00f3n tanto ex vivo como in vivo.<\/div>\n
Es importante destacar que la plataforma de fabricaci\u00f3n de VIVEbiotech es la misma para lotes de Ingenier\u00eda de Desarrollo y GMP.<\/div>\n
\n
El Departamento de Desarrollo de Upstream desarrolla tareas como:<\/div>\n
\n
    \n
  • Ajustes en el proceso inicial de expansi\u00f3n celular o seedtrain.<\/li>\n
  • Definici\u00f3n de condiciones \u00f3ptimas de siembra de los biorreactores.<\/li>\n
  • Selecci\u00f3n de las mejores condiciones para llevar a cabo la transfecci\u00f3n.<\/li>\n
  • Definici\u00f3n de la duraci\u00f3n y condiciones \u00f3ptimas para recolectar el harvest.<\/li>\n
  • Determinaci\u00f3n de los Controles Durante Proceso (IPCs, In-Process Control).<\/li>\n
  • Testado de nuevas tecnolog\u00edas con el objetivo continuo de aumentar la productividad durante el USP.<\/li>\n<\/ul>\n<\/div>\n
    \n
    \n

    El Departamento de Desarrollo de Downstream lleva a cabo trabajos como:<\/p>\n<\/div>\n

    \n
      \n
    • Optimizaci\u00f3n del proceso cromatogr\u00e1fico.<\/li>\n
    • Ajustes en el proceso de la filtraci\u00f3n tangencial (TFF, tangential flow filtration).<\/li>\n
    • Desarrollo de mejor aproximaci\u00f3n de llenado (F&F, Fill & Finish).<\/li>\n
    • Determinaci\u00f3n de los Controles Durante Proceso (IPCs, In-Process Control).<\/li>\n
    • Testado de nuevas tecnolog\u00edas con el objetivo continuo de aumentar la productividad durante el DSP.<\/li>\n<\/ul>\n<\/div>\n
      Una vez concluida nuestra estrategia de desarrollo y optimizaci\u00f3n, nuestro objetivo final es transferir estas mejoras a los servicios ofertados para beneficio de nuestros\/as clientes\/as.<\/div>\n


      \n<\/p>\n","protected":false},"excerpt":{"rendered":"

      VIVEbiotech cuenta con departamentos de optimizaci\u00f3n de proceso tanto de producci\u00f3n (UPS, upstream) y purificaci\u00f3n (DSP, downstream).<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":21,"menu_order":20,"comment_status":"closed","ping_status":"closed","template":"views\/optimizacion.blade.php","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-174","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nOptimizaci\u00f3n - VIVEbiotech<\/title>\n<meta name=\"description\" content=\"VIVEbiotech cuenta con departamentos de optimizaci\u00f3n de proceso tanto para la producci\u00f3n Upstream como para la purificaci\u00f3n Downstream.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.vivebiotech.com\/es\/tecnologia\/optimizacion\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Optimizaci\u00f3n - 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